Meloxicam
Action
Indications
Contraindications
Route/Dosage
Interactions
Adverse Reactions
Precautions
Patient Care Considerations
Administration/Storage
Assessment/Interventions
Patient/Family Education
(mell-ox-ih-kam)
Mobic
Class: Analgesic/NSAID
Action Decreases inflammation, pain, and fever, probably through inhibition of cyclooxygenase activity and prostaglandin synthesis.
Indications Relief of signs and symptoms of osteoarthritis.
Contraindications Hypersensitivity to aspirin or any other NSAID.
Route/Dosage
7.5 to 15 mg once daily (maximum 15 mg/day).
Interactions
ACE inhibitors (eg, captopril): Antihypertensive effects may be decreased. Aspirin: Additive GI toxicity. Cholestyramine: Plasma levels of meloxicam may be reduced. Loop diuretics (eg, furosemide), thiazide diuretics (eg, chlorothiazide): Diuretic effects may be decreased. Lithium: May increase lithium levels. Warfarin: May increase risk of gastric erosion and bleeding. Lab Test Interferences: None well documented.
Adverse Reactions
CV: Arrhythmia; palpitation; tachycardia. DERM: Rash; pruritus; alopecia; angioedema; bullous eruption; erythema multiforme; photosensitivity; Stevens-Johnson syndrome; sweating; toxic epidermal necrolysis; urticaria. EENT: Pharyngitis; esophagitis; abnormal vision; conjunctivitis; taste perversion; innitus. GI: Abdominal pain; diarrhea; nausea; constipation; dyspepsia; flatulence; omiting; colitis; dry mouth; duodenal ulcer; eructation; gastric ulcer; intestinal perforation; melena; pancreatitis; perforated duodenal and gastric ulcers; lcerative stomatitis. GU: Micturition frequency; urinary tract infection; albuminuria; increased BUN and creatinine; hematuria; interstitial nephritis; renal failure. HEMA: Anemia; agranulocytosis; leukopenia; purpura; thrombocytopenia; ilirubinemia. HEPA: Increased ALT and AST; hepatitis; jaundice; liver failure. META: Edema; dehydration. RESP: Upper respiratory tract infection; coughing; asthma; bronchospasm; yspnea. OTHER: Falling; flu-like symptoms; pain; arthralgia; back pain; anaphylactoid reactions.
Precautions
Pregnancy: Category C. Lactation: Undetermined. Children: Safety and efficacy not established. Elderly: Use with caution. Cardiovascular disease: Since fluid retention and edema can occur; use with caution in patients with fluid retention, hypertension, or heart failure. GI effects: Serious GI toxicity (eg, bleeding, ulceration, perforation) can occur at any time, with or without warning signs. Hepatic impairment: Assess liver function while on therapy. Renal impairment: Assess function before and during therapy because NSAID metabolites are eliminated by the kidney.
PATIENT CARE CONSIDERATIONS
Administration/Storage
Assessment/Interventions
OVERDOSAGE: SIGNS & SYMPTOMS
Lethargy, drowsiness, nausea, vomiting, epigastric pain, GI bleeding, hypertension, acute renal failure, hepatic dysfunction, respiratory depression, coma, convulsions, cardiovascular collapse, cardiac arrest
Patient/Family Education
Справочник препаратов (англ.) / M
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